The show's format is that of educational PBS children's television shows such as Sesame Street and The Electric Company (e.g. use of stock footage, puppetry, and clips of children being interviewed), parodying the format in a very adult-oriented manner under the slogan "Play School on Acid". In addition to general controversial comedy, it satirizes politics, religion, war, sex, and culture with black comedy.
Wonder Showzen was originally developed and pitched to the USA Network, but after a few minutes of viewing, executives there quickly concluded it did not fit the network's programming style. However, Viacom was re-branding MTV2 and made Wonder Showzen part of its new programming lineup. It aired as part of Sic 'Em Fridays, along with Dirty Sanchez and Wildboyz. The pilot was named simply "Kids Show". The Wonder Showzen theme song is still 'Kids Show'. Reruns of the show have aired on MTV and Comedy Central.
MTV released the first season of Wonder Showzen on DVD March 28, 2006. The second season of Wonder Showzen premiered on March 31, 2006 and had its season-two finale starring Clarence on May 19, 2006 on MTV2. This season was released on DVD October 10, 2006, with an easter egg that featured an animation contest. The grand prize was announced as the winner's animation appearing on "the next DVD", but the creators later said a third season was unlikely, and MTV afterward canceled the show. A return is even more unlikely as the creators of Wonder Showzen moved on to the animated series Xavier: Renegade Angel.